Synthesis and characterization of polymer-coated magnetic nanoparticles
Abstract
Magnetic nanoparticles (MNPs) synthesized by a co-precipitation method of Fe2+ and Fe3+ in basic solution were coated with poly[(methacrylic acid)-ran-(2-methacryloyloxyethyl phosphorylcholine)] (PMAMPC-MNPs) via a chelation between a carboxyl group of PMAMPC and an iron atom. Polymer concentration and chelation time were optimized. The success of PMAMPC-MNPs preparation was confirmed by FT-IR. TEM results showed that the PMAMPC-MNPs were spherical with the size of 10 to 50 nm. Dried PMAMPC-MNPs were easily dispersed and stable in aqueous media. Moreover, PMAMPC-MNPs hold their catalytic activity for the reaction of 3,3',5,5'-tetramethylbenzidine (TMB) in a presence of H2O2 to produce blue color products. This result indicated that they are potential to use for colorimetric biosensors application.References
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